In recent decades, the most common means by which couples regulate fertility have changed from methods requiring control or cooperation by men, e.g., condoms, withdrawal and periodic abstinence, to those for which women bear primary responsibility e.g., virtually all-reversible modern methods.

While the world's major killer disease, smallpox, that used to claim millions of lives has been eliminated, the planet has been struck with a more dreaded disease, AIDS or Acquired Immuno Deficiency Syndrome.