Infertility has been relatively neglected as both a health problem and a subject for social science research in South Asia, as in the developing world more generally. The general thrust of both programmes and research has been on the correlates of high fertility and its regulation rather than on

India's efforts to promote family planning have produced a significant increase in the couple protection rate (CPR) which has increased by about 33 percent during the last 22 years-from 10.4 percent in 1970 to 43.5 in 1992.

After Ritter and Hinkelmann, Kirk and his Colleagues Kirk also reported that in matings where the father is in-compatible with the mother with respect to the ABO groups, the children show a higher frequency of the Hp1 gene.